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Page 1
RNAi screens identify CHD4 as an essential gene in breast cancer growth.
D'Alesio C, Punzi S, Cicalese A, Fornasari L, Furia L, Riva L, Carugo A, Curigliano G, Criscitiello C, Pruneri G, Pelicci PG, Faretta M, Bossi D, Lanfrancone L. D'Alesio C, et al. Oncotarget. 2016 Dec 6;7(49):80901-80915. doi: 10.18632/oncotarget.12646. Oncotarget. 2016. PMID: 27779108 Free PMC article.
The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.
Sanarico AG, Ronchini C, Croce A, Memmi EM, Cammarata UA, De Antoni A, Lavorgna S, Divona M, Giacò L, Melloni GEM, Brendolan A, Simonetti G, Martinelli G, Mancuso P, Bertolini F, Coco FL, Melino G, Pelicci PG, Bernassola F. Sanarico AG, et al. Leukemia. 2018 Apr;32(4):911-919. doi: 10.1038/leu.2017.342. Epub 2017 Dec 6. Leukemia. 2018. PMID: 29209041 Free PMC article.
In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.
Bossi D, Cicalese A, Dellino GI, Luzi L, Riva L, D'Alesio C, Diaferia GR, Carugo A, Cavallaro E, Piccioni R, Barberis M, Mazzarol G, Testori A, Punzi S, Pallavicini I, Tosti G, Giacó L, Melloni G, Heffernan TP, Natoli G, Draetta GF, Minucci S, Pelicci P, Lanfrancone L. Bossi D, et al. Cancer Discov. 2016 Jun;6(6):650-63. doi: 10.1158/2159-8290.CD-15-1200. Epub 2016 May 13. Cancer Discov. 2016. PMID: 27179036
Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth.
Di Malta C, Siciliano D, Calcagni A, Monfregola J, Punzi S, Pastore N, Eastes AN, Davis O, De Cegli R, Zampelli A, Di Giovannantonio LG, Nusco E, Platt N, Guida A, Ogmundsdottir MH, Lanfrancone L, Perera RM, Zoncu R, Pelicci PG, Settembre C, Ballabio A. Di Malta C, et al. Science. 2017 Jun 16;356(6343):1188-1192. doi: 10.1126/science.aag2553. Science. 2017. PMID: 28619945 Free PMC article.