Abstract
Using a protein microarray, a broad spectrum of autoantibodies were demonstrated in patients with either Wiskott-Aldrich syndrome (WAS) or with X-linked thrombocytopenia (XLT), indicating that immune dysregulation is an integral component of both diseases.
Publication types
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Letter
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Antibody Diversity
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Autoantibodies / blood
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Autoantibodies / immunology*
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Autoantigens / immunology
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Child
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Child, Preschool
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Epitopes
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Female
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Genetic Diseases, X-Linked / genetics
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Genetic Diseases, X-Linked / immunology*
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Humans
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Infant
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Male
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Middle Aged
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Quality of Life
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Thrombocytopenia / genetics
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Thrombocytopenia / immunology*
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Wiskott-Aldrich Syndrome / genetics
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Wiskott-Aldrich Syndrome / immunology*
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Wiskott-Aldrich Syndrome Protein Family / genetics*
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Young Adult
Substances
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Autoantibodies
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Autoantigens
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Epitopes
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Wiskott-Aldrich Syndrome Protein Family