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Direct activation of full-length proapoptotic BAK.
Leshchiner ES, Braun CR, Bird GH, Walensky LD. Leshchiner ES, et al. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):E986-95. doi: 10.1073/pnas.1214313110. Epub 2013 Feb 12. Proc Natl Acad Sci U S A. 2013. PMID: 23404709 Free PMC article.
A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.
LaBelle JL, Katz SG, Bird GH, Gavathiotis E, Stewart ML, Lawrence C, Fisher JK, Godes M, Pitter K, Kung AL, Walensky LD. LaBelle JL, et al. J Clin Invest. 2012 Jun;122(6):2018-31. doi: 10.1172/JCI46231. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622039 Free PMC article.
Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism.
Barclay LA, Wales TE, Garner TP, Wachter F, Lee S, Guerra RM, Stewart ML, Braun CR, Bird GH, Gavathiotis E, Engen JR, Walensky LD. Barclay LA, et al. Mol Cell. 2015 Mar 5;57(5):873-886. doi: 10.1016/j.molcel.2015.01.014. Epub 2015 Feb 12. Mol Cell. 2015. PMID: 25684204 Free PMC article.
11 results