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Adrenergic signaling regulates mitochondrial Ca2+ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca2+ uniporter.
O-Uchi J, Jhun BS, Xu S, Hurst S, Raffaello A, Liu X, Yi B, Zhang H, Gross P, Mishra J, Ainbinder A, Kettlewell S, Smith GL, Dirksen RT, Wang W, Rizzuto R, Sheu SS. O-Uchi J, et al. Antioxid Redox Signal. 2014 Aug 20;21(6):863-79. doi: 10.1089/ars.2013.5394. Epub 2014 Jun 25. Antioxid Redox Signal. 2014. PMID: 24800979 Free PMC article.
Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca2+-induced ATP production in cardiac H9c2 myoblasts.
O-Uchi J, Jhun BS, Hurst S, Bisetto S, Gross P, Chen M, Kettlewell S, Park J, Oyamada H, Smith GL, Murayama T, Sheu SS. O-Uchi J, et al. Am J Physiol Heart Circ Physiol. 2013 Dec;305(12):H1736-51. doi: 10.1152/ajpheart.00094.2013. Epub 2013 Oct 11. Am J Physiol Heart Circ Physiol. 2013. PMID: 24124188 Free PMC article.