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Zidovudine (AZT) monotherapy selects for the A360V mutation in the connection domain of HIV-1 reverse transcriptase.
PLoS One. 2012;7(2):e31558. doi: 10.1371/journal.pone.0031558. Epub 2012 Feb 21.
PLoS One. 2012.
PMID: 22363673
Free PMC article.
Clinical Trial.
Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase.
Brehm JH, Lalama CM, Hughes MD, Haubrich R, Riddler SA, Sluis-Cremer N, Mellors JW; AIDS Clinical Trials Group Study A5142 Protocol Team.
Brehm JH, et al.
J Acquir Immune Defic Syndr. 2011 Apr;56(4):344-8. doi: 10.1097/QAI.0b013e31820cf029.
J Acquir Immune Defic Syndr. 2011.
PMID: 21350368
Free PMC article.
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