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Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity.
Marques P, Villarroel-Vicente C, Collado A, García A, Vila L, Duplan I, Hennuyer N, Garibotto F, Enriz RD, Dacquet C, Staels B, Piqueras L, Cortes D, Sanz MJ, Cabedo N. Marques P, et al. Pharmacol Res. 2023 Jan;187:106638. doi: 10.1016/j.phrs.2022.106638. Epub 2022 Dec 28. Pharmacol Res. 2023. PMID: 36586645 Free article.
Electrothermal patches driving the transdermal delivery of insulin.
Pagneux Q, Ye R, Chengnan L, Barras A, Hennuyer N, Staels B, Caina D, Osses JIA, Abderrahmani A, Plaisance V, Pawlowski V, Boukherroub R, Melinte S, Szunerits S. Pagneux Q, et al. Nanoscale Horiz. 2020 Apr 1;5(4):663-670. doi: 10.1039/c9nh00576e. Epub 2020 Jan 2. Nanoscale Horiz. 2020. PMID: 32226966
The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids.
Ducastel S, Touche V, Trabelsi MS, Boulinguiez A, Butruille L, Nawrot M, Peschard S, Chávez-Talavera O, Dorchies E, Vallez E, Annicotte JS, Lancel S, Briand O, Bantubungi K, Caron S, Bindels LB, Delzenne NM, Tailleux A, Staels B, Lestavel S. Ducastel S, et al. Sci Rep. 2020 Jan 13;10(1):174. doi: 10.1038/s41598-019-56743-x. Sci Rep. 2020. PMID: 31932631 Free PMC article.
Transcriptional Network Analysis Implicates Altered Hepatic Immune Function in NASH development and resolution.
Haas JT, Vonghia L, Mogilenko DA, Verrijken A, Molendi-Coste O, Fleury S, Deprince A, Nikitin A, Woitrain E, Ducrocq-Geoffroy L, Pic S, Derudas B, Dehondt H, Gheeraert C, Van Gaal L, Driessen A, Lefebvre P, Staels B, Francque S, Dombrowicz D. Haas JT, et al. Nat Metab. 2019 Jun;1(6):604-614. doi: 10.1038/s42255-019-0076-1. Epub 2019 Jun 14. Nat Metab. 2019. PMID: 31701087 Free PMC article.
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis.
Dehondt H, Marino A, Butruille L, Mogilenko DA, Nzoussi Loubota AC, Chávez-Talavera O, Dorchies E, Vallez E, Haas J, Derudas B, Bongiovanni A, Tardivel M, Kuipers F, Lefebvre P, Lestavel S, Tailleux A, Dombrowicz D, Caron S, Staels B. Dehondt H, et al. Mol Metab. 2023 Mar;69:101686. doi: 10.1016/j.molmet.2023.101686. Epub 2023 Feb 4. Mol Metab. 2023. PMID: 36746333 Free PMC article.
12 results