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2020 2
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Page 1
Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization.
Henry A, Gordillo-Marañón M, Finan C, Schmidt AF, Ferreira JP, Karra R, Sundström J, Lind L, Ärnlöv J, Zannad F, Mälarstig A, Hingorani AD, Lumbers RT; HERMES and SCALLOP Consortia. Henry A, et al. Circulation. 2022 Apr 19;145(16):1205-1217. doi: 10.1161/CIRCULATIONAHA.121.056663. Epub 2022 Mar 18. Circulation. 2022. PMID: 35300523 Free PMC article.
Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study.
Hamilton FW, Thomas M, Arnold D, Palmer T, Moran E, Mentzer AJ, Maskell N, Baillie K, Summers C, Hingorani A, MacGowan A, Khandaker GM, Mitchell R, Davey Smith G, Ghazal P, Timpson NJ. Hamilton FW, et al. PLoS Med. 2023 Jan 30;20(1):e1004174. doi: 10.1371/journal.pmed.1004174. eCollection 2023 Jan. PLoS Med. 2023. PMID: 36716318 Free PMC article.
Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study.
Kuan V, Denaxas S, Patalay P, Nitsch D, Mathur R, Gonzalez-Izquierdo A, Sofat R, Partridge L, Roberts A, Wong ICK, Hingorani M, Chaturvedi N, Hemingway H, Hingorani AD; Multimorbidity Mechanism and Therapeutic Research Collaborative (MMTRC). Kuan V, et al. Lancet Digit Health. 2023 Jan;5(1):e16-e27. doi: 10.1016/S2589-7500(22)00187-X. Epub 2022 Nov 29. Lancet Digit Health. 2023. PMID: 36460578 Free article.
Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Pietzner M, Wheeler E, Carrasco-Zanini J, Raffler J, Kerrison ND, Oerton E, Auyeung VPW, Luan J, Finan C, Casas JP, Ostroff R, Williams SA, Kastenmüller G, Ralser M, Gamazon ER, Wareham NJ, Hingorani AD, Langenberg C. Pietzner M, et al. Nat Commun. 2020 Dec 16;11(1):6397. doi: 10.1038/s41467-020-19996-z. Nat Commun. 2020. PMID: 33328453 Free PMC article.
Genetic drug target validation using Mendelian randomisation.
Schmidt AF, Finan C, Gordillo-Marañón M, Asselbergs FW, Freitag DF, Patel RS, Tyl B, Chopade S, Faraway R, Zwierzyna M, Hingorani AD. Schmidt AF, et al. Nat Commun. 2020 Jun 26;11(1):3255. doi: 10.1038/s41467-020-16969-0. Nat Commun. 2020. PMID: 32591531 Free PMC article.
T2 and T2 mapping and weighted imaging in cardiac MRI.
Topriceanu CC, Pierce I, Moon JC, Captur G. Topriceanu CC, et al. Magn Reson Imaging. 2022 Nov;93:15-32. doi: 10.1016/j.mri.2022.07.012. Epub 2022 Jul 30. Magn Reson Imaging. 2022. PMID: 35914654 Free article. Review.
Arterial pulse wave modeling and analysis for vascular-age studies: a review from VascAgeNet.
Alastruey J, Charlton PH, Bikia V, Paliakaite B, Hametner B, Bruno RM, Mulder MP, Vennin S, Piskin S, Khir AW, Guala A, Mayer CC, Mynard J, Hughes AD, Segers P, Westerhof BE. Alastruey J, et al. Am J Physiol Heart Circ Physiol. 2023 Jul 1;325(1):H1-H29. doi: 10.1152/ajpheart.00705.2022. Epub 2023 Mar 31. Am J Physiol Heart Circ Physiol. 2023. PMID: 37000606 Free PMC article. Review.
NMR metabolomic modeling of age and lifespan: A multicohort analysis.
Lau CE, Manou M, Markozannes G, Ala-Korpela M, Ben-Shlomo Y, Chaturvedi N, Engmann J, Gentry-Maharaj A, Herzig KH, Hingorani A, Järvelin MR, Kähönen M, Kivimäki M, Lehtimäki T, Marttila S, Menon U, Munroe PB, Palaniswamy S, Providencia R, Raitakari O, Schmidt AF, Sebert S, Wong A, Vineis P, Tzoulaki I, Robinson O. Lau CE, et al. Aging Cell. 2024 Jul;23(7):e14164. doi: 10.1111/acel.14164. Epub 2024 Apr 18. Aging Cell. 2024. PMID: 38637937 Free PMC article.
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