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Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation.
Biochem Pharmacol. 1996 Aug 23;52(4):527-34. doi: 10.1016/0006-2952(96)00303-6.
Biochem Pharmacol. 1996.
PMID: 8759024
Differential immune responses to alpha-gal epitopes on xenografts and allografts: implications for accommodation in xenotransplantation.
Tanemura M, Yin D, Chong AS, Galili U.
Tanemura M, et al.
J Clin Invest. 2000 Feb;105(3):301-10. doi: 10.1172/JCI7358.
J Clin Invest. 2000.
PMID: 10675356
Free PMC article.
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In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice.
Xu X, Blinder L, Shen J, Gong H, Finnegan A, Williams JW, Chong AS.
Xu X, et al.
J Immunol. 1997 Jul 1;159(1):167-74.
J Immunol. 1997.
PMID: 9200452
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