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Page 1
Dual anti-HIV mechanism of clofarabine.
Daly MB, Roth ME, Bonnac L, Maldonado JO, Xie J, Clouser CL, Patterson SE, Kim B, Mansky LM. Daly MB, et al. Retrovirology. 2016 Mar 24;13:20. doi: 10.1186/s12977-016-0254-0. Retrovirology. 2016. PMID: 27009333 Free PMC article.
Substrates and Inhibitors of SAMHD1.
Hollenbaugh JA, Shelton J, Tao S, Amiralaei S, Liu P, Lu X, Goetze RW, Zhou L, Nettles JH, Schinazi RF, Kim B. Hollenbaugh JA, et al. PLoS One. 2017 Jan 3;12(1):e0169052. doi: 10.1371/journal.pone.0169052. eCollection 2017. PLoS One. 2017. PMID: 28046007 Free PMC article.
SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.
Thientosapol ES, Bosnjak D, Durack T, Stevanovski I, van Geldermalsen M, Holst J, Jahan Z, Shepard C, Weninger W, Kim B, Brink R, Jolly CJ. Thientosapol ES, et al. Proc Natl Acad Sci U S A. 2018 May 8;115(19):4921-4926. doi: 10.1073/pnas.1719771115. Epub 2018 Apr 18. Proc Natl Acad Sci U S A. 2018. PMID: 29669924 Free PMC article.
SAMHD1 prevents autoimmunity by maintaining genome stability.
Kretschmer S, Wolf C, König N, Staroske W, Guck J, Häusler M, Luksch H, Nguyen LA, Kim B, Alexopoulou D, Dahl A, Rapp A, Cardoso MC, Shevchenko A, Lee-Kirsch MA. Kretschmer S, et al. Ann Rheum Dis. 2015 Mar;74(3):e17. doi: 10.1136/annrheumdis-2013-204845. Epub 2014 Jan 20. Ann Rheum Dis. 2015. PMID: 24445253 Free PMC article.
SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia.
Johansson P, Klein-Hitpass L, Choidas A, Habenberger P, Mahboubi B, Kim B, Bergmann A, Scholtysik R, Brauser M, Lollies A, Siebert R, Zenz T, Dührsen U, Küppers R, Dürig J. Johansson P, et al. Blood Cancer J. 2018 Jan 19;8(1):11. doi: 10.1038/s41408-017-0036-5. Blood Cancer J. 2018. PMID: 29352181 Free PMC article. Clinical Trial.
Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.
Behrendt R, Schumann T, Gerbaulet A, Nguyen LA, Schubert N, Alexopoulou D, Berka U, Lienenklaus S, Peschke K, Gibbert K, Wittmann S, Lindemann D, Weiss S, Dahl A, Naumann R, Dittmer U, Kim B, Mueller W, Gramberg T, Roers A. Behrendt R, et al. Cell Rep. 2013 Aug 29;4(4):689-96. doi: 10.1016/j.celrep.2013.07.037. Epub 2013 Aug 22. Cell Rep. 2013. PMID: 23972988 Free PMC article.
Restriction of diverse retroviruses by SAMHD1.
Gramberg T, Kahle T, Bloch N, Wittmann S, Müllers E, Daddacha W, Hofmann H, Kim B, Lindemann D, Landau NR. Gramberg T, et al. Retrovirology. 2013 Mar 5;10:26. doi: 10.1186/1742-4690-10-26. Retrovirology. 2013. PMID: 23497255 Free PMC article.
77 results