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An hour after immunization peritoneal B-1 cells are activated to migrate to lymphoid organs where within 1 day they produce IgM antibodies that initiate elicitation of contact sensitivity.
J Immunol. 2005 Dec 1;175(11):7170-8. doi: 10.4049/jimmunol.175.11.7170.
J Immunol. 2005.
PMID: 16301620
IL-12 reverses established antigen-specific tolerance of contact sensitivity by affecting costimulatory molecules B7-1 (CD80) and B7-2 (CD86).
Ushio H, Tsuji RF, Szczepanik M, Kawamoto K, Matsuda H, Askenase PW.
Ushio H, et al.
J Immunol. 1998 Mar 1;160(5):2080-8.
J Immunol. 1998.
PMID: 9498744
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