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The cell envelope glycoconjugates of Mycobacterium tuberculosis.
Angala SK, Belardinelli JM, Huc-Claustre E, Wheat WH, Jackson M. Angala SK, et al. Crit Rev Biochem Mol Biol. 2014 Sep-Oct;49(5):361-99. doi: 10.3109/10409238.2014.925420. Epub 2014 Jun 10. Crit Rev Biochem Mol Biol. 2014. PMID: 24915502 Free PMC article. Review.
The structure-activity relationship of urea derivatives as anti-tuberculosis agents.
Brown JR, North EJ, Hurdle JG, Morisseau C, Scarborough JS, Sun D, Korduláková J, Scherman MS, Jones V, Grzegorzewicz A, Crew RM, Jackson M, McNeil MR, Lee RE. Brown JR, et al. Bioorg Med Chem. 2011 Sep 15;19(18):5585-95. doi: 10.1016/j.bmc.2011.07.034. Epub 2011 Jul 24. Bioorg Med Chem. 2011. PMID: 21840723 Free PMC article.
A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.
Grzegorzewicz AE, Korduláková J, Jones V, Born SE, Belardinelli JM, Vaquié A, Gundi VA, Madacki J, Slama N, Laval F, Vaubourgeix J, Crew RM, Gicquel B, Daffé M, Morbidoni HR, Brennan PJ, Quémard A, McNeil MR, Jackson M. Grzegorzewicz AE, et al. J Biol Chem. 2012 Nov 9;287(46):38434-41. doi: 10.1074/jbc.M112.400994. Epub 2012 Sep 21. J Biol Chem. 2012. PMID: 23002234 Free PMC article.
Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.
Scherman MS, North EJ, Jones V, Hess TN, Grzegorzewicz AE, Kasagami T, Kim IH, Merzlikin O, Lenaerts AJ, Lee RE, Jackson M, Morisseau C, McNeil MR. Scherman MS, et al. Bioorg Med Chem. 2012 May 15;20(10):3255-62. doi: 10.1016/j.bmc.2012.03.058. Epub 2012 Mar 31. Bioorg Med Chem. 2012. PMID: 22522007 Free PMC article.