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Activation of Aurora-A kinase by protein partner binding and phosphorylation are independent and synergistic.
J Biol Chem. 2012 Jan 6;287(2):1150-7. doi: 10.1074/jbc.M111.312090. Epub 2011 Nov 16.
J Biol Chem. 2012.
PMID: 22094468
Free PMC article.
Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design.
Dodson CA, Kosmopoulou M, Richards MW, Atrash B, Bavetsias V, Blagg J, Bayliss R.
Dodson CA, et al.
Biochem J. 2010 Mar 15;427(1):19-28. doi: 10.1042/BJ20091530.
Biochem J. 2010.
PMID: 20067443
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