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Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer's disease.
Huang Y, Wang M, Ni H, Zhang J, Li A, Hu B, Junqueira Alves C, Wahane S, Rios de Anda M, Ho L, Li Y, Kang S, Neff R, Kostic A, Buxbaum JD, Crary JF, Brennand KJ, Zhang B, Zou H, Friedel RH. Huang Y, et al. Nat Neurosci. 2024 Aug;27(8):1489-1504. doi: 10.1038/s41593-024-01664-w. Epub 2024 May 27. Nat Neurosci. 2024. PMID: 38802590
Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2.
Junqueira Alves C, Hannah T, Sadia S, Kolsteeg C, Dixon A, Wiener RJ, Nguyen H, Tipping MJ, Silva Ladeira J, Fernandes da Costa Franklin P, de Paula Dutra de Nigro N, Alves Dias R, Zabala Capriles PV, Rodrigues Furtado de Mendonça JP, Slesinger PA, Costa KD, Zou H, Friedel RH. Junqueira Alves C, et al. Nat Commun. 2025 Jan 2;16(1):272. doi: 10.1038/s41467-024-55056-6. Nat Commun. 2025. PMID: 39747004 Free PMC article.