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PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways.
Free Radic Biol Med. 2008 Dec 15;45(12):1695-704. doi: 10.1016/j.freeradbiomed.2008.09.002. Epub 2008 Sep 17.
Free Radic Biol Med. 2008.
PMID: 18852043
Free PMC article.
The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation.
Ramanan S, Kooshki M, Zhao W, Hsu FC, Riddle DR, Robbins ME.
Ramanan S, et al.
Int J Radiat Oncol Biol Phys. 2009 Nov 1;75(3):870-7. doi: 10.1016/j.ijrobp.2009.06.059.
Int J Radiat Oncol Biol Phys. 2009.
PMID: 19801103
Free PMC article.
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