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Page 1
The molecular basis of leukemia.
Gilliland DG, Jordan CT, Felix CA. Gilliland DG, et al. Hematology Am Soc Hematol Educ Program. 2004:80-97. doi: 10.1182/asheducation-2004.1.80. Hematology Am Soc Hematol Educ Program. 2004. PMID: 15561678 Review.
Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.
Lovett BD, Lo Nigro L, Rappaport EF, Blair IA, Osheroff N, Zheng N, Megonigal MD, Williams WR, Nowell PC, Felix CA. Lovett BD, et al. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9802-7. doi: 10.1073/pnas.171309898. Epub 2001 Aug 7. Proc Natl Acad Sci U S A. 2001. PMID: 11493704 Free PMC article.
1,4-Benzoquinone is a topoisomerase II poison.
Lindsey RH Jr, Bromberg KD, Felix CA, Osheroff N. Lindsey RH Jr, et al. Biochemistry. 2004 Jun 15;43(23):7563-74. doi: 10.1021/bi049756r. Biochemistry. 2004. PMID: 15182198
MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site.
Slater DJ, Hilgenfeld E, Rappaport EF, Shah N, Meek RG, Williams WR, Lovett BD, Osheroff N, Autar RS, Ried T, Felix CA. Slater DJ, et al. Oncogene. 2002 Jul 11;21(30):4706-14. doi: 10.1038/sj.onc.1205572. Oncogene. 2002. PMID: 12096348
DNA topoisomerase II in therapy-related acute promyelocytic leukemia.
Mistry AR, Felix CA, Whitmarsh RJ, Mason A, Reiter A, Cassinat B, Parry A, Walz C, Wiemels JL, Segal MR, Adès L, Blair IA, Osheroff N, Peniket AJ, Lafage-Pochitaloff M, Cross NC, Chomienne C, Solomon E, Fenaux P, Grimwade D. Mistry AR, et al. N Engl J Med. 2005 Apr 14;352(15):1529-38. doi: 10.1056/NEJMoa042715. N Engl J Med. 2005. PMID: 15829534 Free article.
18 results