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Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.
Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1667-72. doi: 10.1073/pnas.1110730109. Epub 2012 Jan 17.
Proc Natl Acad Sci U S A. 2012.
PMID: 22307628
Free PMC article.
Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation.
Wendel AA, Cooper DE, Ilkayeva OR, Muoio DM, Coleman RA.
Wendel AA, et al.
J Biol Chem. 2013 Sep 20;288(38):27299-27306. doi: 10.1074/jbc.M113.485219. Epub 2013 Aug 1.
J Biol Chem. 2013.
PMID: 23908354
Free PMC article.
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