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Hepatitis C virus-specific immune responses and quasi-species variability at baseline are associated with nonresponse to antiviral therapy during advanced hepatitis C.
Morishima C, Polyak SJ, Ray R, Doherty MC, Di Bisceglie AM, Malet PF, Bonkovsky HL, Sullivan DG, Gretch DR, Rothman AL, Koziel MJ, Lindsay KL; Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis Trial Group. Morishima C, et al. J Infect Dis. 2006 Apr 1;193(7):931-40. doi: 10.1086/500952. Epub 2006 Feb 22. J Infect Dis. 2006. PMID: 16518754 Clinical Trial.