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Selenium detoxification is required for cancer-cell survival.
Carlisle AE, Lee N, Matthew-Onabanjo AN, Spears ME, Park SJ, Youkana D, Doshi MB, Peppers A, Li R, Joseph AB, Smith M, Simin K, Zhu LJ, Greer PL, Shaw LM, Kim D. Carlisle AE, et al. Nat Metab. 2020 Jul;2(7):603-611. doi: 10.1038/s42255-020-0224-7. Epub 2020 Jul 6. Nat Metab. 2020. PMID: 32694795 Free PMC article.
De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.
Spears ME, Lee N, Hwang S, Park SJ, Carlisle AE, Li R, Doshi MB, Armando AM, Gao J, Simin K, Zhu LJ, Greer PL, Quehenberger O, Torres EM, Kim D. Spears ME, et al. Cell Rep. 2022 Sep 27;40(13):111415. doi: 10.1016/j.celrep.2022.111415. Cell Rep. 2022. PMID: 36170811 Free PMC article.