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2021 3
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Page 1
Viral and host mediators of non-suppressible HIV-1 viremia.
Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Crain CR, Traunbauer AK, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, Jilg N, Kaseke C, Giguel F, Lian X, Deo R, Gillespie E, Chishti R, Abrha S, Adams T, Siagian A, Dorazio D, Anderson PL, Deeks SG, Lederman MM, Yawetz S, Kuritzkes DR, Lichterfeld MD, Sieg S, Tsibris A, Carrington M, Brumme ZL, Castillo-Mancilla JR, Engelman AN, Gaiha GD, Li JZ. Mohammadi A, et al. Nat Med. 2023 Dec;29(12):3212-3223. doi: 10.1038/s41591-023-02611-1. Epub 2023 Nov 13. Nat Med. 2023. PMID: 37957382 Free PMC article.
SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency.
Li Y, Choudhary MC, Regan J, Boucau J, Nathan A, Speidel T, Liew MY, Edelstein GE, Kawano Y, Uddin R, Deo R, Marino C, Getz MA, Reynolds Z, Barry M, Gilbert RF, Tien D, Sagar S, Vyas TD, Flynn JP, Hammond SP, Novack LA, Choi B, Cernadas M, Wallace ZS, Sparks JA, Vyas JM, Seaman MS, Gaiha GD, Siedner MJ, Barczak AK, Lemieux JE, Li JZ. Li Y, et al. Sci Transl Med. 2024 Jan 24;16(731):eadk1599. doi: 10.1126/scitranslmed.adk1599. Epub 2024 Jan 24. Sci Transl Med. 2024. PMID: 38266109 Free PMC article.
Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses.
Nathan A, Rossin EJ, Kaseke C, Park RJ, Khatri A, Koundakjian D, Urbach JM, Singh NK, Bashirova A, Tano-Menka R, Senjobe F, Waring MT, Piechocka-Trocha A, Garcia-Beltran WF, Iafrate AJ, Naranbhai V, Carrington M, Walker BD, Gaiha GD. Nathan A, et al. Cell. 2021 Aug 19;184(17):4401-4413.e10. doi: 10.1016/j.cell.2021.06.029. Epub 2021 Jun 30. Cell. 2021. PMID: 34265281 Free PMC article.
Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia.
Collins DR, Urbach JM, Racenet ZJ, Arshad U, Power KA, Newman RM, Mylvaganam GH, Ly NL, Lian X, Rull A, Rassadkina Y, Yanez AG, Peluso MJ, Deeks SG, Vidal F, Lichterfeld M, Yu XG, Gaiha GD, Allen TM, Walker BD. Collins DR, et al. Immunity. 2021 Oct 12;54(10):2372-2384.e7. doi: 10.1016/j.immuni.2021.08.007. Epub 2021 Sep 7. Immunity. 2021. PMID: 34496223 Free PMC article.
Identification of mouse CD4+ T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers.
Bricio-Moreno L, Barreto de Albuquerque J, Neary JM, Nguyen T, Kuhn LF, Yeung Y, Hastie KM, Landeras-Bueno S, Olmedillas E, Hariharan C, Nathan A, Getz MA, Gayton AC, Khatri A, Gaiha GD, Ollmann Saphire E, Luster AD, Moon JJ. Bricio-Moreno L, et al. Front Immunol. 2024 Mar 11;15:1329846. doi: 10.3389/fimmu.2024.1329846. eCollection 2024. Front Immunol. 2024. PMID: 38529279 Free PMC article.
SARS-CoV-2 Viral Clearance and Evolution Varies by Extent of Immunodeficiency.
Li Y, Choudhary MC, Regan J, Boucau J, Nathan A, Speidel T, Liew MY, Edelstein GE, Kawano Y, Uddin R, Deo R, Marino C, Getz MA, Reynold Z, Barry M, Gilbert RF, Tien D, Sagar S, Vyas TD, Flynn JP, Hammond SP, Novack LA, Choi B, Cernadas M, Wallace ZS, Sparks JA, Vyas JM, Seaman MS, Gaiha GD, Siedner MJ, Barczak AK, Lemieux JE, Li JZ. Li Y, et al. medRxiv [Preprint]. 2023 Aug 7:2023.07.31.23293441. doi: 10.1101/2023.07.31.23293441. medRxiv. 2023. Update in: Sci Transl Med. 2024 Jan 24;16(731):eadk1599. doi: 10.1126/scitranslmed.adk1599 PMID: 37577493 Free PMC article. Updated. Preprint.
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals.
Naranbhai V, Nathan A, Kaseke C, Berrios C, Khatri A, Choi S, Getz MA, Tano-Menka R, Ofoman O, Gayton A, Senjobe F, Zhao Z, St Denis KJ, Lam EC, Carrington M, Garcia-Beltran WF, Balazs AB, Walker BD, Iafrate AJ, Gaiha GD. Naranbhai V, et al. Cell. 2022 Mar 17;185(6):1041-1051.e6. doi: 10.1016/j.cell.2022.01.029. Epub 2022 Feb 3. Cell. 2022. PMID: 35202566 Free PMC article.
Identification of mouse CD4+ T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers.
Moreno LB, de Albuquerque JB, Neary JM, Nguyen T, Hastie KM, Landeras-Bueno S, Hariharan C, Nathan A, Getz MA, Gayton AC, Khatri A, Gaiha GD, Saphire EO, Luster AD, Moon JJ. Moreno LB, et al. bioRxiv [Preprint]. 2023 Nov 17:2023.11.16.566918. doi: 10.1101/2023.11.16.566918. bioRxiv. 2023. Update in: Front Immunol. 2024 Mar 11;15:1329846. doi: 10.3389/fimmu.2024.1329846 PMID: 38014059 Free PMC article. Updated. Preprint.
Polymorphic residues in HLA-B that mediate HIV control distinctly modulate peptide interactions with both TCR and KIR molecules.
Tano-Menka R, Singh NK, Muzhingi I, Li X, Mandanas MV, Kaseke C, Crain CR, Zhang A, Ogunshola FJ, Vecchiarello L, Piechocka-Trocha A, Bashirova A, Birnbaum ME, Carrington M, Walker BD, Gaiha GD. Tano-Menka R, et al. Structure. 2024 Aug 8;32(8):1121-1136.e5. doi: 10.1016/j.str.2024.04.015. Epub 2024 May 10. Structure. 2024. PMID: 38733995 Free PMC article.
12 results