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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9.
Cell. 2022.
PMID: 35688146
Free PMC article.
Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states.
Southard KM, Ardy RC, Tang A, O'Sullivan DD, Metzner E, Guruvayurappan K, Norman TM.
Southard KM, et al.
bioRxiv [Preprint]. 2024 Aug 3:2024.07.31.606073. doi: 10.1101/2024.07.31.606073.
bioRxiv. 2024.
PMID: 39131349
Free PMC article.
Preprint.
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Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome.
Metzner E, Southard KM, Norman TM.
Metzner E, et al.
bioRxiv [Preprint]. 2024 Jul 27:2024.07.26.605307. doi: 10.1101/2024.07.26.605307.
bioRxiv. 2024.
PMID: 39091800
Free PMC article.
Preprint.
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