DP5 OD021345/OD/NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	2
2017	2
2018	1
2019	1
2020	4
2021	3
2023	1
2024	0

1

Yeast surface display platform for rapid discovery of conformationally selective nanobodies.

McMahon C, Baier AS, Pascolutti R, Wegrecki M, Zheng S, Ong JX, Erlandson SC, Hilger D, Rasmussen SGF, Ring AM, Manglik A, Kruse AC. McMahon C, et al. Nat Struct Mol Biol. 2018 Mar;25(3):289-296. doi: 10.1038/s41594-018-0028-6. Epub 2018 Feb 12. Nat Struct Mol Biol. 2018. PMID: 29434346 Free PMC article.

2

Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling.

Paek J, Kalocsay M, Staus DP, Wingler L, Pascolutti R, Paulo JA, Gygi SP, Kruse AC. Paek J, et al. Cell. 2017 Apr 6;169(2):338-349.e11. doi: 10.1016/j.cell.2017.03.028. Cell. 2017. PMID: 28388415 Free PMC article.

3

Rapid generation of potent antibodies by autonomous hypermutation in yeast.

Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4. Epub 2021 Jun 24. Nat Chem Biol. 2021. PMID: 34168368 Free PMC article.

4

Antibodies Expand the Scope of Angiotensin Receptor Pharmacology.

Skiba MA, Sterling SM, Rawson S, Gilman MSA, Xu H, Nemeth GR, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Wingler LM, Kruse AC. Skiba MA, et al. bioRxiv [Preprint]. 2023 Aug 24:2023.08.23.554128. doi: 10.1101/2023.08.23.554128. bioRxiv. 2023. Update in: Nat Chem Biol. 2024 May 14. doi: 10.1038/s41589-024-01620-6. PMID: 37662341 Free PMC article. Updated. Preprint.

5

Protein design and variant prediction using autoregressive generative models.

Shin JE, Riesselman AJ, Kollasch AW, McMahon C, Simon E, Sander C, Manglik A, Kruse AC, Marks DS. Shin JE, et al. Nat Commun. 2021 Apr 23;12(1):2403. doi: 10.1038/s41467-021-22732-w. Nat Commun. 2021. PMID: 33893299 Free PMC article.

6

Mapping and engineering the interaction between adiponectin and T-cadherin.

Pascolutti R, Erlandson SC, Burri DJ, Zheng S, Kruse AC. Pascolutti R, et al. J Biol Chem. 2020 Feb 28;295(9):2749-2759. doi: 10.1074/jbc.RA119.010970. Epub 2020 Jan 8. J Biol Chem. 2020. PMID: 31915248 Free PMC article.

7

Identification of the gene that codes for the σ₂ receptor.

Alon A, Schmidt HR, Wood MD, Sahn JJ, Martin SF, Kruse AC. Alon A, et al. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7160-7165. doi: 10.1073/pnas.1705154114. Epub 2017 May 30. Proc Natl Acad Sci U S A. 2017. PMID: 28559337 Free PMC article.

8

Synthetic nanobodies as angiotensin receptor blockers.

McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ. McMahon C, et al. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20284-20291. doi: 10.1073/pnas.2009029117. Epub 2020 Aug 4. Proc Natl Acad Sci U S A. 2020. PMID: 32753386 Free PMC article.

9

Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81.

Susa KJ, Rawson S, Kruse AC, Blacklow SC. Susa KJ, et al. Science. 2021 Jan 15;371(6526):300-305. doi: 10.1126/science.abd9836. Science. 2021. PMID: 33446559 Free PMC article.

10

Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.

Pascolutti R, Sun X, Kao J, Maute RL, Ring AM, Bowman GR, Kruse AC. Pascolutti R, et al. Structure. 2016 Oct 4;24(10):1719-1728. doi: 10.1016/j.str.2016.06.026. Epub 2016 Sep 8. Structure. 2016. PMID: 27618663 Free PMC article.

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