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Metabolic inflexibility promotes mitochondrial health during liver regeneration.
Science. 2024 Jun 14;384(6701):eadj4301. doi: 10.1126/science.adj4301. Epub 2024 Jun 14.
Science. 2024.
PMID: 38870309
Free PMC article.
Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.
Deja S, Fletcher JA, Kim CW, Kucejova B, Fu X, Mizerska M, Villegas M, Pudelko-Malik N, Browder N, Inigo-Vollmer M, Menezes CJ, Mishra P, Berglund ED, Browning JD, Thyfault JP, Young JD, Horton JD, Burgess SC.
Deja S, et al.
Cell Metab. 2024 May 7;36(5):1088-1104.e12. doi: 10.1016/j.cmet.2024.02.004. Epub 2024 Mar 5.
Cell Metab. 2024.
PMID: 38447582
Free article.
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Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.
Shelton SD, House S, Martins Nascentes Melo L, Ramesh V, Chen Z, Wei T, Wang X, Llamas CB, Venigalla SSK, Menezes CJ, Allies G, Krystkiewicz J, Rösler J, Meckelmann SW, Zhao P, Rambow F, Schadendorf D, Zhao Z, Gill JG, DeBerardinis RJ, Morrison SJ, Tasdogan A, Mishra P.
Shelton SD, et al.
Sci Adv. 2024 Nov;10(44):eadk8801. doi: 10.1126/sciadv.adk8801. Epub 2024 Nov 1.
Sci Adv. 2024.
PMID: 39485847
Free PMC article.
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