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Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes.
Paudel BB, Tan SF, Fox TE, Ung J, Golla U, Shaw JJP, Dunton W, Lee I, Fares WA, Patel S, Sharma A, Viny AD, Barth BM, Tallman MS, Cabot M, Garrett-Bakelman FE, Levine RL, Kester M, Feith DJ, Claxton D, Janes KA, Loughran TP Jr. Paudel BB, et al. Blood Adv. 2024 Mar 12;8(5):1137-1142. doi: 10.1182/bloodadvances.2023010535. Blood Adv. 2024. PMID: 38170742 Free PMC article. No abstract available.
A fluorogenic substrate for the detection of lipid amidases in intact cells.
Casasampere M, Ung J, Iñáñez A, Dufau C, Tsuboi K, Casas J, Tan SF, Feith DJ, Andrieu-Abadie N, Segui B, Loughran TP Jr, Abad JL, Fabrias G. Casasampere M, et al. J Lipid Res. 2024 Mar;65(3):100520. doi: 10.1016/j.jlr.2024.100520. Epub 2024 Feb 17. J Lipid Res. 2024. PMID: 38369184 Free PMC article.
Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes.
Paudel BB, Tan SF, Fox TE, Ung J, Shaw J, Dunton W, Lee I, Sharma A, Viny AD, Barth BM, Tallman MS, Cabot M, Garrett-Bakelman FE, Levine RL, Kester M, Claxton D, Feith DJ, Janes KA, Loughran TP Jr. Paudel BB, et al. bioRxiv [Preprint]. 2023 Apr 17:2023.04.13.536805. doi: 10.1101/2023.04.13.536805. bioRxiv. 2023. Update in: Blood Adv. 2024 Mar 12;8(5):1137-1142. doi: 10.1182/bloodadvances.2023010535. PMID: 37131653 Free PMC article. Updated. Preprint.
Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia.
Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP Jr, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, Claxton DF, Shaw JJP, Bhowmick D, Cabot MC. Fisher-Wellman KH, et al. Cancers (Basel). 2023 Mar 21;15(6):1883. doi: 10.3390/cancers15061883. Cancers (Basel). 2023. PMID: 36980769 Free PMC article.