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Dnmt3a regulates T-cell development and suppresses T-ALL transformation.
Kramer AC, Kothari A, Wilson WC, Celik H, Nikitas J, Mallaney C, Ostrander EL, Eultgen E, Martens A, Valentine MC, Young AL, Druley TE, Figueroa ME, Zhang B, Challen GA. Kramer AC, et al. Leukemia. 2017 Nov;31(11):2479-2490. doi: 10.1038/leu.2017.89. Epub 2017 Mar 21. Leukemia. 2017. PMID: 28321121 Free PMC article.
Txnip Enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells via p21.
Zhang CR, Ostrander EL, Kukhar O, Mallaney C, Sun J, Haussler E, Celik H, Koh WK, King KY, Gontarz P, Challen GA. Zhang CR, et al. Blood Cancer Discov. 2022 May 5;3(3):220-239. doi: 10.1158/2643-3230.BCD-21-0132. Blood Cancer Discov. 2022. PMID: 35394496 Free PMC article.