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Page 1
IMPDH dysregulation in disease: a mini review.
Burrell AL, Kollman JM. Burrell AL, et al. Biochem Soc Trans. 2022 Feb 28;50(1):71-82. doi: 10.1042/BST20210446. Biochem Soc Trans. 2022. PMID: 35191957 Free PMC article. Review.
Freedom of assembly: metabolic enzymes come together.
Simonet JC, Burrell AL, Kollman JM, Peterson JR. Simonet JC, et al. Mol Biol Cell. 2020 Jun 1;31(12):1201-1205. doi: 10.1091/mbc.E18-10-0675. Mol Biol Cell. 2020. PMID: 32463766 Free PMC article.
Point mutations in IMPDH2 which cause early-onset neurodevelopmental disorders disrupt enzyme regulation and filament structure.
O'Neill AG, Burrell AL, Zech M, Elpeleg O, Harel T, Edvardson S, Shaked HM, Rippert AL, Nomakuchi T, Izumi K, Kollman JM. O'Neill AG, et al. bioRxiv [Preprint]. 2023 Mar 15:2023.03.15.532669. doi: 10.1101/2023.03.15.532669. bioRxiv. 2023. Update in: J Biol Chem. 2023 Aug;299(8):105012. doi: 10.1016/j.jbc.2023.105012 PMID: 36993700 Free PMC article. Updated. Preprint.
Light-sensitive phosphorylation regulates enzyme activity and filament assembly of human IMPDH1 retinal splice variants.
Calise SJ, O'Neill AG, Burrell AL, Dickinson MS, Molfino J, Clarke C, Quispe J, Sokolov D, Buey RM, Kollman JM. Calise SJ, et al. bioRxiv [Preprint]. 2023 Sep 21:2023.09.21.558867. doi: 10.1101/2023.09.21.558867. bioRxiv. 2023. Update in: J Cell Biol. 2024 Apr 1;223(4):e202310139. doi: 10.1083/jcb.202310139 PMID: 37790411 Free PMC article. Updated. Preprint.
BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Witus SR, Burrell AL, Farrell DP, Kang J, Wang M, Hansen JM, Pravat A, Tuttle LM, Stewart MD, Brzovic PS, Chatterjee C, Zhao W, DiMaio F, Kollman JM, Klevit RE. Witus SR, et al. Nat Struct Mol Biol. 2021 Mar;28(3):268-277. doi: 10.1038/s41594-020-00556-4. Epub 2021 Feb 15. Nat Struct Mol Biol. 2021. PMID: 33589814 Free PMC article.