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Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.
Proc Natl Acad Sci U S A. 2017 May 9;114(19):5029-5034. doi: 10.1073/pnas.1700477114. Epub 2017 Apr 24.
Proc Natl Acad Sci U S A. 2017.
PMID: 28438992
Free PMC article.
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
Minami SS, Min SW, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME, Mucke L, Farese RV Jr, Gan L.
Minami SS, et al.
Nat Med. 2014 Oct;20(10):1157-64. doi: 10.1038/nm.3672. Epub 2014 Sep 28.
Nat Med. 2014.
PMID: 25261995
Free PMC article.
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Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
Minami SS, Shen V, Le D, Krabbe G, Asgarov R, Perez-Celajes L, Lee CH, Li J, Donnelly-Roberts D, Gan L.
Minami SS, et al.
Biochem Pharmacol. 2015 Oct 15;97(4):454-462. doi: 10.1016/j.bcp.2015.07.016. Epub 2015 Jul 20.
Biochem Pharmacol. 2015.
PMID: 26206194
Free PMC article.
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