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2025

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2025 0

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Page 1
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.
Tajan M, Hennequart M, Cheung EC, Zani F, Hock AK, Legrave N, Maddocks ODK, Ridgway RA, Athineos D, Suárez-Bonnet A, Ludwig RL, Novellasdemunt L, Angelis N, Li VSW, Vlachogiannis G, Valeri N, Mainolfi N, Suri V, Friedman A, Manfredi M, Blyth K, Sansom OJ, Vousden KH. Tajan M, et al. Nat Commun. 2021 Jan 14;12(1):366. doi: 10.1038/s41467-020-20223-y. Nat Commun. 2021. PMID: 33446657 Free PMC article.
Taking up the reins of power: metabolic functions of p53.
Humpton T, Vousden KH. Humpton T, et al. J Mol Cell Biol. 2019 Jul 19;11(7):610-614. doi: 10.1093/jmcb/mjz065. J Mol Cell Biol. 2019. PMID: 31282931 Free PMC article. Review. No abstract available.
Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Magnussen HM, Ahmed SF, Sibbet GJ, Hristova VA, Nomura K, Hock AK, Archibald LJ, Jamieson AG, Fushman D, Vousden KH, Weissman AM, Huang DT. Magnussen HM, et al. Nat Commun. 2020 Apr 29;11(1):2094. doi: 10.1038/s41467-020-15783-y. Nat Commun. 2020. PMID: 32350255 Free PMC article.