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HACE1 is a potential tumor suppressor in osteosarcoma.
El-Naggar AM, Clarkson PW, Negri GL, Turgu B, Zhang F, Anglesio MS, Sorensen PH. El-Naggar AM, et al. Cell Death Dis. 2019 Jan 8;10(1):21. doi: 10.1038/s41419-018-1276-4. Cell Death Dis. 2019. PMID: 30622235 Free PMC article.
HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Kogler M, Tortola L, Negri GL, Leopoldi A, El-Naggar AM, Mereiter S, Gomez-Diaz C, Nitsch R, Tortora D, Kavirayani AM, Gapp BV, Rao S, Uribesalgo I, Hoffmann D, Cikes D, Novatchkova M, Williams DA, Trent JM, Ikeda F, Daugaard M, Hagelkruys A, Sorensen PH, Penninger JM. Kogler M, et al. Cancer Res. 2020 Jul 15;80(14):3009-3022. doi: 10.1158/0008-5472.CAN-19-2270. Epub 2020 May 4. Cancer Res. 2020. PMID: 32366477 Free PMC article.