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Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting.
Wiklander OP, Nordin JZ, O'Loughlin A, Gustafsson Y, Corso G, Mäger I, Vader P, Lee Y, Sork H, Seow Y, Heldring N, Alvarez-Erviti L, Smith CI, Le Blanc K, Macchiarini P, Jungebluth P, Wood MJ, Andaloussi SE. Wiklander OP, et al. J Extracell Vesicles. 2015 Apr 20;4:26316. doi: 10.3402/jev.v4.26316. eCollection 2015. J Extracell Vesicles. 2015. PMID: 25899407 Free PMC article.
Exosome-mediated delivery of siRNA in vitro and in vivo.
El-Andaloussi S, Lee Y, Lakhal-Littleton S, Li J, Seow Y, Gardiner C, Alvarez-Erviti L, Sargent IL, Wood MJ. El-Andaloussi S, et al. Nat Protoc. 2012 Dec;7(12):2112-26. doi: 10.1038/nprot.2012.131. Epub 2012 Nov 15. Nat Protoc. 2012. PMID: 23154783
Targeting RNA to treat neuromuscular disease.
Muntoni F, Wood MJ. Muntoni F, et al. Nat Rev Drug Discov. 2011 Aug 1;10(8):621-37. doi: 10.1038/nrd3459. Nat Rev Drug Discov. 2011. PMID: 21804598 Review.
30 results