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ERp57 does not require interactions with calnexin and calreticulin to promote assembly of class I histocompatibility molecules, and it enhances peptide loading independently of its redox activity.
Zhang Y, Kozlov G, Pocanschi CL, Brockmeier U, Ireland BS, Maattanen P, Howe C, Elliott T, Gehring K, Williams DB. Zhang Y, et al. J Biol Chem. 2009 Apr 10;284(15):10160-73. doi: 10.1074/jbc.M808356200. Epub 2009 Feb 5. J Biol Chem. 2009. PMID: 19196713 Free PMC article.