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The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J. Gozani O, et al. Cell. 2003 Jul 11;114(1):99-111. doi: 10.1016/s0092-8674(03)00480-x. Cell. 2003. PMID: 12859901 Free article.
Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockout mice.
Scheid MP, Huber M, Damen JE, Hughes M, Kang V, Neilsen P, Prestwich GD, Krystal G, Duronio V. Scheid MP, et al. J Biol Chem. 2002 Mar 15;277(11):9027-35. doi: 10.1074/jbc.M106755200. Epub 2002 Jan 7. J Biol Chem. 2002. PMID: 11781306 Free article.