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Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice.
Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM. Gregorius J, et al. Basic Res Cardiol. 2021 Jun 8;116(1):40. doi: 10.1007/s00395-021-00881-9. Basic Res Cardiol. 2021. PMID: 34105014 Free PMC article.
Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion.
Tuz AA, Ghosh S, Karsch L, Ttoouli D, Sata SP, Ulusoy Ö, Kraus A, Hoerenbaum N, Wolf JN, Lohmann S, Zwirnlein F, Kaygusuz V, Lakovic V, Tummes HL, Beer A, Gallert M, Thiebes S, Qefalia A, Cibir Z, Antler M, Korste S, Haj Yehia E, Michel L, Rassaf T, Kaltwasser B, Abdelrahman H, Mohamud Yusuf A, Wang C, Yin D, Haeusler L, Lueong S, Richter M, Engel DR, Stenzel M, Soehnlein O, Frank B, Solo-Nomenjanahary M, Ho-Tin-Noé B, Siveke JT, Totzeck M, Hoffmann D, Grüneboom A, Hagemann N, Hasenberg A, Desilles JP, Mazighi M, Sickmann A, Chen J, Hermann DM, Gunzer M, Singh V. Tuz AA, et al. Nat Cardiovasc Res. 2024 May;3(5):525-540. doi: 10.1038/s44161-024-00462-8. Epub 2024 Apr 23. Nat Cardiovasc Res. 2024. PMID: 39195931 Free PMC article.
Hypocaloric Diet Initiated Post-Ischemia Provides Long-Term Neuroprotection and Promotes Peri-Infarct Brain Remodeling by Regulating Metabolic and Survival-Promoting Proteins.
de Carvalho TS, Sanchez-Mendoza EH, Schultz Moreira AR, Nascentes Melo LM, Wang C, Sardari M, Hagemann N, Doeppner TR, Kleinschnitz C, Hermann DM. de Carvalho TS, et al. Mol Neurobiol. 2021 Apr;58(4):1491-1503. doi: 10.1007/s12035-020-02207-7. Epub 2020 Nov 17. Mol Neurobiol. 2021. PMID: 33200399 Free PMC article.