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Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD.
Benjamin JT, Plosa EJ, Sucre JM, van der Meer R, Dave S, Gutor S, Nichols DS, Gulleman PM, Jetter CS, Han W, Xin M, Dinella PC, Catanzarite A, Kook S, Dolma K, Lal CV, Gaggar A, Blalock JE, Newcomb DC, Richmond BW, Kropski JA, Young LR, Guttentag SH, Blackwell TS. Benjamin JT, et al. J Clin Invest. 2021 Jan 4;131(1):e139481. doi: 10.1172/JCI139481. J Clin Invest. 2021. PMID: 33108351 Free PMC article.
Interferon-dependent signaling is critical for viral clearance in airway neutrophils.
Margaroli C, Fram T, Sharma NS, Patel SB, Tipper J, Robison SW, Russell DW, Fortmann SD, Banday MM, Soto-Vazquez Y, Abdalla T, Saitornuang S, Madison MC, Leal SM Jr, Harrod KS, Erdmann NB, Gaggar A. Margaroli C, et al. JCI Insight. 2023 May 22;8(10):e167042. doi: 10.1172/jci.insight.167042. JCI Insight. 2023. PMID: 37071484 Free PMC article.
An in vivo model for extracellular vesicle-induced emphysema.
Margaroli C, Madison MC, Viera L, Russell DW, Gaggar A, Genschmer KR, Blalock JE. Margaroli C, et al. JCI Insight. 2022 Jan 25;7(4):e153560. doi: 10.1172/jci.insight.153560. JCI Insight. 2022. PMID: 35077395 Free PMC article.
Type I interferon-dependent IFIT3 signaling is critical for viral clearance in airway neutrophils.
Margaroli C, Fram T, Sharma NS, Patel SB, Tipper J, Robison SW, Russell DW, Fortmann SD, Banday MM, Abdalla T, Saitornuang S, Madison MC, Leal SM Jr, Harrod KS, Erdmann NB, Gaggar A. Margaroli C, et al. Res Sq [Preprint]. 2023 Mar 21:rs.3.rs-1812836. doi: 10.21203/rs.3.rs-1812836/v1. Res Sq. 2023. Update in: JCI Insight. 2023 May 22;8(10):e167042. doi: 10.1172/jci.insight.167042 PMID: 36993474 Free PMC article. Updated. Preprint.
Prevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease.
Tran TV, Kinney GL, Comellas A, Hoth KF, Baldomero AK, Mamary AJ, Curtis JL, Hanania N, Casaburi R, Young KA, Kim V, Make B, Wan ES, Diaz AA, Hokanson J, Crapo JD, Silverman EK, Bhatt SP, Regan E, Fortis S; COPDGene® Investigators – Core Units; COPDGene® Investigators – Clinical Centers. Tran TV, et al. Respir Med. 2023 Mar;208:107126. doi: 10.1016/j.rmed.2023.107126. Epub 2023 Jan 28. Respir Med. 2023. PMID: 36717002 Free PMC article.
16 results