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Vero cell-adapted SARS-CoV-2 strain shows increased viral growth through furin-mediated efficient spike cleavage.
Minami S, Kotaki T, Sakai Y, Okamura S, Torii S, Ono C, Motooka D, Hamajima R, Nouda R, Nurdin JA, Yamasaki M, Kanai Y, Ebina H, Maeda Y, Okamoto T, Tachibana T, Matsuura Y, Kobayashi T. Minami S, et al. Microbiol Spectr. 2024 Apr 2;12(4):e0285923. doi: 10.1128/spectrum.02859-23. Epub 2024 Feb 28. Microbiol Spectr. 2024. PMID: 38415690 Free PMC article.
Intratracheal trimerized nanobody cocktail administration suppresses weight loss and prolongs survival of SARS-CoV-2 infected mice.
Nagata K, Utsumi D, Asaka MN, Maeda R, Shirakawa K, Kazuma Y, Nomura R, Horisawa Y, Yanagida Y, Kawai Y, Sato K, Yamaoka Y, Miyakawa K, Ryo A, Yasutomi Y, Imura A, Takaori-Kondo A. Nagata K, et al. Commun Med (Lond). 2022 Nov 26;2(1):152. doi: 10.1038/s43856-022-00213-5. Commun Med (Lond). 2022. PMID: 36435945 Free PMC article.
Characterization of a neutralizing antibody that recognizes a loop region adjacent to the receptor-binding interface of the SARS-CoV-2 spike receptor-binding domain.
Anzai I, Fujita J, Ono C, Kosaka Y, Miyamoto Y, Shichinohe S, Takada K, Torii S, Taguwa S, Suzuki K, Makino F, Kajita T, Inoue T, Namba K, Watanabe T, Matsuura Y. Anzai I, et al. Microbiol Spectr. 2024 Apr 2;12(4):e0365523. doi: 10.1128/spectrum.03655-23. Epub 2024 Feb 28. Microbiol Spectr. 2024. PMID: 38415660 Free PMC article.