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HIV Diagnostics and Vaccines: It Takes Two to Tango.
Colón W, Oriol-Mathieu V, Hural J, Hattingh L, Adungo F, Lagatie O, Lavreys L, Allen M, Anzala O, Espy N, Fransen K, Garcia PJ, Maciel M Jr, Murtagh M, Peel SA, Peeling RW, Tan LLJ, Warren M, Pau MG, D'Souza PM. Colón W, et al. J Infect Dis. 2024 Jun 14;229(6):1919-1925. doi: 10.1093/infdis/jiae113. J Infect Dis. 2024. PMID: 38451247 Review.
Current serologic tests for HIV screening and confirmation of infection present challenges to the adoption of HIV vaccines. The detection of vaccine-induced HIV-1 antibodies in the absence of HIV-1 infection, referred to as vaccine-induced seropositivity/sero …
Current serologic tests for HIV screening and confirmation of infection present challenges to the adoption of HIV vaccines. The detec …
Concomitant Administration of Ad26.RSV.preF/RSV preF Protein Vaccine and High-Dose Influenza Vaccine in Adults 65 Years and Older: A Noninferiority Trial.
Widagdo W, Bastian AR, Jastorff AM, Scheys I, De Paepe E, Comeaux CA, Ligtenberg N, Callendret B, Heijnen E. Widagdo W, et al. J Infect Dis. 2024 Aug 16;230(2):e374-e383. doi: 10.1093/infdis/jiad594. J Infect Dis. 2024. PMID: 38134393 Free PMC article. Clinical Trial.
RESULTS: Coadministered Ad26.RSV.preF/RSV preF protein and Fluzone-HD vaccines induced noninferior immune responses compared to each vaccine administered alone. Seroconversion and seroprotection rates against influenza were similar between groups. Both vaccines …
RESULTS: Coadministered Ad26.RSV.preF/RSV preF protein and Fluzone-HD vaccines induced noninferior immune responses compared to each …
Safety and Humoral Immunogenicity of Different Dose Levels of Ad26.COV2.S as a 2-Dose Regimen in COVID-19 Vaccine-Naive Healthy Adults: A Phase 3 Randomized Clinical Trial.
Rezelj VV, Paddenburg F, Diegbe ME, Nangosyah J, Reisinger EC, Hu W, Truyers C, Scheper G, Le Gars M, Hendriks J, Struyf F, Douoguih M, Schuitemaker H, Ruiz-Guiñazú J. Rezelj VV, et al. Vaccines (Basel). 2024 Oct 3;12(10):1136. doi: 10.3390/vaccines12101136. Vaccines (Basel). 2024. PMID: 39460303 Free PMC article.
CONCLUSIONS: This study highlights the challenges associated with conducting clinical studies in a rapidly evolving environment and underscores the importance of platform data that can guide initial vaccine specifications such as shelf life during accelerated vaccine …
CONCLUSIONS: This study highlights the challenges associated with conducting clinical studies in a rapidly evolving environment and undersco …