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The ubiquitination status of the glucagon receptor determines signal bias.
Kaur S, Sokrat B, Capozzi ME, El K, Bai Y, Jazic A, Han B, Krishna Kumar K, D'Alessio DA, Campbell JE, Bouvier M, Shenoy SK. Kaur S, et al. J Biol Chem. 2023 May;299(5):104690. doi: 10.1016/j.jbc.2023.104690. Epub 2023 Apr 8. J Biol Chem. 2023. PMID: 37037304 Free PMC article.
Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress.
Fadzeyeva E, Locatelli CAA, Trzaskalski NA, Nguyen MA, Capozzi ME, Vulesevic B, Morrow NM, Ghorbani P, Hanson AA, Lorenzen-Schmidt I, Doyle MA, Seymour R, Varin EM, Fullerton MD, Campbell JE, Mulvihill EE. Fadzeyeva E, et al. iScience. 2023 Apr 26;26(5):106748. doi: 10.1016/j.isci.2023.106748. eCollection 2023 May 19. iScience. 2023. PMID: 37216093 Free PMC article.