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Th17-mediated inflammation in asthma.
Newcomb DC, Peebles RS Jr. Newcomb DC, et al. Curr Opin Immunol. 2013 Dec;25(6):755-60. doi: 10.1016/j.coi.2013.08.002. Epub 2013 Sep 11. Curr Opin Immunol. 2013. PMID: 24035139 Free PMC article. Review.
PGI2 as a regulator of inflammatory diseases.
Dorris SL, Peebles RS Jr. Dorris SL, et al. Mediators Inflamm. 2012;2012:926968. doi: 10.1155/2012/926968. Epub 2012 Jul 18. Mediators Inflamm. 2012. PMID: 22851816 Free PMC article. Review.
Estrogen and progesterone decrease let-7f microRNA expression and increase IL-23/IL-23 receptor signaling and IL-17A production in patients with severe asthma.
Newcomb DC, Cephus JY, Boswell MG, Fahrenholz JM, Langley EW, Feldman AS, Zhou W, Dulek DE, Goleniewska K, Woodward KB, Sevin CM, Hamilton RG, Kolls JK, Peebles RS Jr. Newcomb DC, et al. J Allergy Clin Immunol. 2015 Oct;136(4):1025-34.e11. doi: 10.1016/j.jaci.2015.05.046. Epub 2015 Aug 1. J Allergy Clin Immunol. 2015. PMID: 26242299 Free PMC article. Clinical Trial.
IL-13 regulates Th17 secretion of IL-17A in an IL-10-dependent manner.
Newcomb DC, Boswell MG, Huckabee MM, Goleniewska K, Dulek DE, Reiss S, Lukacs NW, Kolls JK, Peebles RS Jr. Newcomb DC, et al. J Immunol. 2012 Feb 1;188(3):1027-35. doi: 10.4049/jimmunol.1102216. Epub 2011 Dec 30. J Immunol. 2012. PMID: 22210911 Free PMC article.