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Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.
He BJ, Joiner ML, Singh MV, Luczak ED, Swaminathan PD, Koval OM, Kutschke W, Allamargot C, Yang J, Guan X, Zimmerman K, Grumbach IM, Weiss RM, Spitz DR, Sigmund CD, Blankesteijn WM, Heymans S, Mohler PJ, Anderson ME. He BJ, et al. Nat Med. 2011 Nov 13;17(12):1610-8. doi: 10.1038/nm.2506. Nat Med. 2011. PMID: 22081025 Free PMC article.
Sarcolemma-localized nNOS is required to maintain activity after mild exercise.
Kobayashi YM, Rader EP, Crawford RW, Iyengar NK, Thedens DR, Faulkner JA, Parikh SV, Weiss RM, Chamberlain JS, Moore SA, Campbell KP. Kobayashi YM, et al. Nature. 2008 Nov 27;456(7221):511-5. doi: 10.1038/nature07414. Epub 2008 Oct 26. Nature. 2008. PMID: 18953332 Free PMC article.