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Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations.
Miller TE, Lareau CA, Verga JA, DePasquale EAK, Liu V, Ssozi D, Sandor K, Yin Y, Ludwig LS, El Farran CA, Morgan DM, Satpathy AT, Griffin GK, Lane AA, Love JC, Bernstein BE, Sankaran VG, van Galen P. Miller TE, et al. Nat Biotechnol. 2022 Jul;40(7):1030-1034. doi: 10.1038/s41587-022-01210-8. Epub 2022 Feb 24. Nat Biotechnol. 2022. PMID: 35210612 Free PMC article.
Chromatin accessibility promotes hematopoietic and leukemia stem cell activity.
Cabal-Hierro L, van Galen P, Prado MA, Higby KJ, Togami K, Mowery CT, Paulo JA, Xie Y, Cejas P, Furusawa T, Bustin M, Long HW, Sykes DB, Gygi SP, Finley D, Bernstein BE, Lane AA. Cabal-Hierro L, et al. Nat Commun. 2020 Mar 16;11(1):1406. doi: 10.1038/s41467-020-15221-z. Nat Commun. 2020. PMID: 32179749 Free PMC article.
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.
Kleppe M, Koche R, Zou L, van Galen P, Hill CE, Dong L, De Groote S, Papalexi E, Hanasoge Somasundara AV, Cordner K, Keller M, Farnoud N, Medina J, McGovern E, Reyes J, Roberts J, Witkin M, Rapaport F, Teruya-Feldstein J, Qi J, Rampal R, Bernstein BE, Bradner JE, Levine RL. Kleppe M, et al. Cancer Cell. 2018 Apr 9;33(4):785-787. doi: 10.1016/j.ccell.2018.03.024. Cancer Cell. 2018. PMID: 29634952 Free PMC article. No abstract available.