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Page 1
Inflammation and Premature Ageing in Chronic Kidney Disease.
Ebert T, Pawelzik SC, Witasp A, Arefin S, Hobson S, Kublickiene K, Shiels PG, Bäck M, Stenvinkel P. Ebert T, et al. Toxins (Basel). 2020 Apr 4;12(4):227. doi: 10.3390/toxins12040227. Toxins (Basel). 2020. PMID: 32260373 Free PMC article. Review.
Persistent low-grade inflammation and premature ageing are hallmarks of the uremic phenotype and contribute to impaired health status, reduced quality of life, and premature mortality in chronic kidney disease (CKD). ...
Persistent low-grade inflammation and premature ageing are hallmarks of the uremic phenotype and contribute to impaired health status …
Lifestyle and incident dementia: A COSMIC individual participant data meta‐analysis.
Van Asbroeck S, Köhler S, van Boxtel MPJ, Lipnicki DM, Crawford JD, Castro-Costa E, Lima-Costa MF, Blay SL, Shifu X, Wang T, Yue L, Lipton RB, Katz MJ, Derby CA, Guerchet M, Preux PM, Mbelesso P, Norton J, Ritchie K, Skoog I, Najar J, Sterner TR, Scarmeas N, Yannakoulia M, Dardiotis T, Rolandi E, Davin A, Rossi M, Gureje O, Ojagbemi A, Bello T, Kim KW, Han JW, Oh DJ, Trompet S, Gussekloo J, Riedel-Heller SG, Röhr S, Pabst A, Shahar S, Rivan NFM, Singh DKA, Jacobsen E, Ganguli M, Hughes T, Haan M, Aiello AE, Ding D, Zhao Q, Xiao Z, Narazaki K, Chen T, Chen S, Ng TP, Gwee X, Gao Q, Brodaty H, Trollor J, Kochan N, Lobo A, Santabárbara J, Gracia-Garcia P, Sachdev PS, Deckers K; for Cohort Studies of Memory in an International Consortium (COSMIC). Van Asbroeck S, et al. Alzheimers Dement. 2024 Jun;20(6):3972-3986. doi: 10.1002/alz.13846. Epub 2024 Apr 27. Alzheimers Dement. 2024. PMID: 38676366 Free PMC article. Italian.
INTRODUCTION: The LIfestyle for BRAin Health (LIBRA) index yields a dementia risk score based on modifiable lifestyle factors and is validated in Western samples. ...
INTRODUCTION: The LIfestyle for BRAin Health (LIBRA) index yields a dementia risk score based on modifiable lifestyle factors and is …
The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact.
Kalaria R, Maestre G, Mahinrad S, Acosta DM, Akinyemi RO, Alladi S, Allegri RF, Arshad F, Babalola DO, Baiyewu O, Bak TH, Bellaj T, Brodie-Mends DK, Carrillo MC, Celestin KK, Damasceno A, de Silva RK, de Silva R, Djibuti M, Dreyer AJ, Ellajosyula R, Farombi TH, Friedland RP, Garza N, Gbessemehlan A, Georgiou EE, Govia I, Grinberg LT, Guerchet M, Gugssa SA, Gumikiriza-Onoria JL, Hogervorst E, Hornberger M, Ibanez A, Ihara M, Issac TG, Jönsson L, Karanja WM, Lee JH, Leroi I, Livingston G, Manes FF, Mbakile-Mahlanza L, Miller BL, Musyimi CW, Mutiso VN, Nakasujja N, Ndetei DM, Nightingale S, Novotni G, Nyamayaro P, Nyame S, Ogeng'o JA, Ogunniyi A, de Oliveira MO, Okubadejo NU, Orrell M, Paddick SM, Pericak-Vance MA, Pirtosek Z, Potocnik FCV, Raman R, Rizig M, Rosselli M, Salokhiddinov M, Satizabal CL, Sepulveda-Falla D, Seshadri S, Sexton CE, Skoog I, George-Hyslop PHS, Suemoto CK, Thapa P, Udeh-Momoh CT, Valcour V, Vance JM, Varghese M, Vera JH, Walker RW, Zetterberg H, Zewde YZ, Ismail O. Kalaria R, et al. Alzheimers Dement. 2024 Jun;20(6):4290-4314. doi: 10.1002/alz.13836. Epub 2024 May 2. Alzheimers Dement. 2024. PMID: 38696263 Free PMC article. Review.
Improving office workers' mental health and cognition: a 3-arm cluster randomized controlled trial targeting physical activity and sedentary behavior in multi-component interventions.
Nooijen CFJ, Blom V, Ekblom Ö, Ekblom MM, Kallings LV. Nooijen CFJ, et al. BMC Public Health. 2019 Mar 5;19(1):266. doi: 10.1186/s12889-019-6589-4. BMC Public Health. 2019. PMID: 30836957 Free PMC article.
BACKGROUND: Physically inactive and sedentary lifestyles are negatively related to both mental health and cognition. For office-workers, who spend two-thirds of their workday sitting, it is important to improve these lifestyles. ...Distal outcomes are self-reported mental …
BACKGROUND: Physically inactive and sedentary lifestyles are negatively related to both mental health and cognition. For office-worke …
Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques.
Edsfeldt A, Swart M, Singh P, Dib L, Sun J, Cole JE, Park I, Al-Sharify D, Persson A, Nitulescu M, Borges PDN, Kassiteridi C, Goddard ME, Lee R, Volkov P, Orho-Melander M, Maegdefessel L, Nilsson J, Udalova I, Goncalves I, Monaco C. Edsfeldt A, et al. Eur Heart J. 2022 May 14;43(19):1864-1877. doi: 10.1093/eurheartj/ehab920. Epub 2022 Feb 9. Eur Heart J. 2022. PMID: 35567557 Free PMC article.
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.
Sommerauer C, Gallardo-Dodd CJ, Savva C, Hases L, Birgersson M, Indukuri R, Shen JX, Carravilla P, Geng K, Nørskov Søndergaard J, Ferrer-Aumatell C, Mercier G, Sezgin E, Korach-André M, Petersson C, Hagström H, Lauschke VM, Archer A, Williams C, Kutter C. Sommerauer C, et al. Mol Syst Biol. 2024 Apr;20(4):374-402. doi: 10.1038/s44320-024-00024-x. Epub 2024 Mar 8. Mol Syst Biol. 2024. PMID: 38459198 Free PMC article.
Blood-based multivariate methylation risk score for cognitive impairment and dementia.
Koetsier J, Cavill R, Reijnders R, Harvey J, Homann J, Kouhsar M, Deckers K, Köhler S, Eijssen LMT, van den Hove DLA, Demuth I, Düzel S; Alzheimer's Disease Neuroimaging Initiative; Smith RG, Smith AR, Burrage J, Walker EM, Shireby G, Hannon E, Dempster E, Frayling T, Mill J, Dobricic V, Johannsen P, Wittig M, Franke A, Vandenberghe R, Schaeverbeke J, Freund-Levi Y, Frölich L, Scheltens P, Teunissen CE, Frisoni G, Blin O, Richardson JC, Bordet R, Engelborghs S, de Roeck E, Martinez-Lage P, Tainta M, Lleó A, Sala I, Popp J, Peyratout G, Verhey F, Tsolaki M, Andreasson U, Blennow K, Zetterberg H, Streffer J, Vos SJB, Lovestone S, Visser PJ, Lill CM, Bertram L, Lunnon K, Pishva E. Koetsier J, et al. Alzheimers Dement. 2024 Oct;20(10):6682-6698. doi: 10.1002/alz.14061. Epub 2024 Aug 28. Alzheimers Dement. 2024. PMID: 39193899 Free PMC article.
Alzheimer's disease genetic risk score and neuroimaging in the FINGER lifestyle trial.
Saadmaan G, Dalmasso MC, Ramirez A, Hiltunen M, Kemppainen N, Lehtisalo J, Mangialasche F, Ngandu T, Rinne J, Soininen H, Stephen R, Kivipelto M, Solomon A. Saadmaan G, et al. Alzheimers Dement. 2024 Jun;20(6):4345-4350. doi: 10.1002/alz.13843. Epub 2024 Apr 22. Alzheimers Dement. 2024. PMID: 38647197 Free PMC article. Clinical Trial.
METHODS: 1260 at-risk older individuals without dementia were randomized to multidomain lifestyle intervention or health advice. N = 126 participants underwent magnetic resonance imaging (MRI), and N = 47 positron emission tomography (PET) scans (Pittsburgh Compund B [PiB] …
METHODS: 1260 at-risk older individuals without dementia were randomized to multidomain lifestyle intervention or health advice. N = …
141 results