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Page 1
Boron-Based Inhibitors of the NLRP3 Inflammasome.
Baldwin AG, Rivers-Auty J, Daniels MJD, White CS, Schwalbe CH, Schilling T, Hammadi H, Jaiyong P, Spencer NG, England H, Luheshi NM, Kadirvel M, Lawrence CB, Rothwell NJ, Harte MK, Bryce RA, Allan SM, Eder C, Freeman S, Brough D. Baldwin AG, et al. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5. doi: 10.1016/j.chembiol.2017.08.011. Epub 2017 Sep 21. Cell Chem Biol. 2017. PMID: 28943355 Free PMC article.
Cloudy with a Chance of Pain: Engagement and Subsequent Attrition of Daily Data Entry in a Smartphone Pilot Study Tracking Weather, Disease Severity, and Physical Activity in Patients With Rheumatoid Arthritis.
Reade S, Spencer K, Sergeant JC, Sperrin M, Schultz DM, Ainsworth J, Lakshminarayana R, Hellman B, James B, McBeth J, Sanders C, Dixon WG. Reade S, et al. JMIR Mhealth Uhealth. 2017 Mar 24;5(3):e37. doi: 10.2196/mhealth.6496. JMIR Mhealth Uhealth. 2017. PMID: 28341616 Free PMC article.
A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity.
Johns A, Scharf DH, Gsaller F, Schmidt H, Heinekamp T, Straßburger M, Oliver JD, Birch M, Beckmann N, Dobb KS, Gilsenan J, Rash B, Bignell E, Brakhage AA, Bromley MJ. Johns A, et al. mBio. 2017 Jul 18;8(4):e01504-16. doi: 10.1128/mBio.01504-16. mBio. 2017. PMID: 28720735 Free PMC article.
Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention.
Chowdhury SK, Liu W, Zi M, Li Y, Wang S, Tsui H, Prehar S, Castro S, Zhang H, Ji Y, Zhang X, Xiao R, Zhang R, Lei M, Cyganek L, Guan K, Millar CB, Liao X, Jain MK, Boyett MR, Cartwright EJ, Shiels HA, Wang X. Chowdhury SK, et al. Circulation. 2017 Feb 14;135(7):683-699. doi: 10.1161/CIRCULATIONAHA.116.022941. Epub 2016 Nov 29. Circulation. 2017. PMID: 27899394
Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo.
Vickers CF, Silva APG, Chakraborty A, Fernandez P, Kurepina N, Saville C, Naranjo Y, Pons M, Schnettger LS, Gutierrez MG, Park S, Kreiswith BN, Perlin DS, Thomas EJ, Cavet JS, Tabernero L. Vickers CF, et al. J Med Chem. 2018 Sep 27;61(18):8337-8352. doi: 10.1021/acs.jmedchem.8b00832. Epub 2018 Sep 10. J Med Chem. 2018. PMID: 30153005 Free PMC article.