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3-Hydroxykynurenine targets kainate receptors to promote defense against infection.
Parada-Kusz M, Clatworthy AE, Goering ER, Blackwood SM, Shigeta JY, Mashin E, Salm EJ, Choi C, Combs S, Lee JSW, Rodriguez-Osorio C, Clish C, Tomita S, Hung DT. Parada-Kusz M, et al. Nat Chem Biol. 2024 Dec;20(12):1586-1596. doi: 10.1038/s41589-024-01635-z. Epub 2024 Jun 19. Nat Chem Biol. 2024. PMID: 38898166
Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography.
Yu Q, Kumata K, Rong J, Chen Z, Yamasaki T, Chen J, Xiao Z, Ishii H, Hiraishi A, Shao T, Zhang Y, Hu K, Xie L, Fujinaga M, Zhao C, Mori W, Collier T, Haider A, Tomita S, Zhang MR, Liang S. Yu Q, et al. J Med Chem. 2022 Jul 14;65(13):9144-9158. doi: 10.1021/acs.jmedchem.2c00377. Epub 2022 Jun 28. J Med Chem. 2022. PMID: 35762919 Free PMC article.
A tryptophan metabolite modulates the host response to bacterial infection via kainate receptors.
Parada-Kusz M, Clatworthy AE, Goering ER, Blackwood SM, Salm EJ, Choi C, Combs S, Lee JSW, Rodriguez-Osorio C, Tomita S, Hung DT. Parada-Kusz M, et al. bioRxiv [Preprint]. 2023 Aug 18:2023.08.16.553532. doi: 10.1101/2023.08.16.553532. bioRxiv. 2023. Update in: Nat Chem Biol. 2024 Dec;20(12):1586-1596. doi: 10.1038/s41589-024-01635-z PMID: 37645903 Free PMC article. Updated. Preprint.
24 results