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"Threshold-crossing": A Useful Way to Establish the Counterfactual in Clinical Trials?
Eichler HG, Bloechl-Daum B, Bauer P, Bretz F, Brown J, Hampson LV, Honig P, Krams M, Leufkens H, Lim R, Lumpkin MM, Murphy MJ, Pignatti F, Posch M, Schneeweiss S, Trusheim M, Koenig F. Eichler HG, et al. Clin Pharmacol Ther. 2016 Dec;100(6):699-712. doi: 10.1002/cpt.515. Epub 2016 Oct 19. Clin Pharmacol Ther. 2016. PMID: 27650716 Free PMC article.
Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO.
Ramanan AV, Hampson LV, Lythgoe H, Jones AP, Hardwick B, Hind H, Jacobs B, Vasileiou D, Wadsworth I, Ambrose N, Davidson J, Ferguson PJ, Herlin T, Kavirayani A, Killeen OG, Compeyrot-Lacassagne S, Laxer RM, Roderick M, Swart JF, Hedrich CM, Beresford MW. Ramanan AV, et al. PLoS One. 2019 Jun 5;14(6):e0215739. doi: 10.1371/journal.pone.0215739. eCollection 2019. PLoS One. 2019. PMID: 31166977 Free PMC article.
Elicitation of expert prior opinion: application to the MYPAN trial in childhood polyarteritis nodosa.
Hampson LV, Whitehead J, Eleftheriou D, Tudur-Smith C, Jones R, Jayne D, Hickey H, Beresford MW, Bracaglia C, Caldas A, Cimaz R, Dehoorne J, Dolezalova P, Friswell M, Jelusic M, Marks SD, Martin N, McMahon AM, Peitz J, van Royen-Kerkhof A, Soylemezoglu O, Brogan PA. Hampson LV, et al. PLoS One. 2015 Mar 30;10(3):e0120981. doi: 10.1371/journal.pone.0120981. eCollection 2015. PLoS One. 2015. PMID: 25822991 Free PMC article.
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