NA/HHMI (HHMI)[Grants and Funding] - Search Results

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m⁶A modification plays an integral role in mRNA stability and translation during pattern-triggered immunity.

Chen T, Greene GH, Motley J, Mwimba M, Luo GZ, Xu G, Karapetyan S, Xiang Y, Liu C, He C, Dong X. Chen T, et al. Proc Natl Acad Sci U S A. 2024 Aug 13;121(33):e2411100121. doi: 10.1073/pnas.2411100121. Epub 2024 Aug 8. Proc Natl Acad Sci U S A. 2024. PMID: 39116132 Free PMC article.

MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity.

Liu Y, Hou D, Chen W, Lu X, Komaniecki GP, Xu Y, Yu T, Zhang SM, Linder ME, Lin H. Liu Y, et al. Proc Natl Acad Sci U S A. 2024 Aug 20;121(34):e2403392121. doi: 10.1073/pnas.2403392121. Epub 2024 Aug 14. Proc Natl Acad Sci U S A. 2024. PMID: 39141356 Free PMC article.

Evolution of the substrate specificity of an RNA ligase ribozyme from phosphorimidazole to triphosphate activation.

DasGupta S, Weiss Z, Nisler C, Szostak JW. DasGupta S, et al. Proc Natl Acad Sci U S A. 2024 Sep 17;121(38):e2407325121. doi: 10.1073/pnas.2407325121. Epub 2024 Sep 13. Proc Natl Acad Sci U S A. 2024. PMID: 39269776 Free PMC article.

Quorum sensing orchestrates parallel cell death pathways in Vibrio cholerae via Type 6 secretion-dependent and -independent mechanisms.

Mashruwala AA, Bassler BL. Mashruwala AA, et al. Proc Natl Acad Sci U S A. 2024 Nov 12;121(46):e2412642121. doi: 10.1073/pnas.2412642121. Epub 2024 Nov 5. Proc Natl Acad Sci U S A. 2024. PMID: 39499633 Free PMC article.

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