OCH 126276/CIHR/Canada[Grants and Funding] - Search Results

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Enhanced suppression of polyclonal CD8⁺25⁺ regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes.

Mu C, Zhang X, Wang L, Xu A, Ahmed KA, Pang X, Chibbar R, Freywald A, Huang J, Zhu Y, Xiang J. Mu C, et al. J Leukoc Biol. 2017 May;101(5):1221-1231. doi: 10.1189/jlb.3A0716-295RR. Epub 2017 Jan 17. J Leukoc Biol. 2017. PMID: 28096300

CD40 agonist converting CTL exhaustion via the activation of the mTORC1 pathway enhances PD-1 antagonist action in rescuing exhausted CTLs in chronic infection.

Xu A, Wang R, Freywald A, Stewart K, Tikoo S, Xu J, Zheng C, Xiang J. Xu A, et al. Biochem Biophys Res Commun. 2017 Mar 11;484(3):662-667. doi: 10.1016/j.bbrc.2017.01.172. Epub 2017 Jan 31. Biochem Biophys Res Commun. 2017. PMID: 28153727

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