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Year Number of Results
2016 2
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2020 10
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60 results

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Page 1
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Bryant KL, Stalnecker CA, Zeitouni D, Klomp JE, Peng S, Tikunov AP, Gunda V, Pierobon M, Waters AM, George SD, Tomar G, Papke B, Hobbs GA, Yan L, Hayes TK, Diehl JN, Goode GD, Chaika NV, Wang Y, Zhang GF, Witkiewicz AK, Knudsen ES, Petricoin EF 3rd, Singh PK, Macdonald JM, Tran NL, Lyssiotis CA, Ying H, Kimmelman AC, Cox AD, Der CJ. Bryant KL, et al. Nat Med. 2019 Apr;25(4):628-640. doi: 10.1038/s41591-019-0368-8. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833752 Free PMC article.
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
Wasko UN, Jiang J, Curiel-Garcia A, Wang Y, Lee B, Orlen M, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Dalton T, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs W, Amparo AA, Hibshman PS, Rees MG, Ronan MM, Roth JA, Bakir B, Badgley MA, Chabot JA, Kluger MD, Manji GA, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Aguirre AJ, Der CJ, Vonderheide RH, Stanger BZ, Singh M, Olive KP. Wasko UN, et al. bioRxiv [Preprint]. 2023 Dec 4:2023.12.03.569791. doi: 10.1101/2023.12.03.569791. bioRxiv. 2023. PMID: 38105998 Free PMC article. Preprint.
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Hobbs GA, Baker NM, Miermont AM, Thurman RD, Pierobon M, Tran TH, Anderson AO, Waters AM, Diehl JN, Papke B, Hodge RG, Klomp JE, Goodwin CM, DeLiberty JM, Wang J, Ng RWS, Gautam P, Bryant KL, Esposito D, Campbell SL, Petricoin EF 3rd, Simanshu DK, Aguirre AJ, Wolpin BM, Wennerberg K, Rudloff U, Cox AD, Der CJ. Hobbs GA, et al. Cancer Discov. 2020 Jan;10(1):104-123. doi: 10.1158/2159-8290.CD-19-1006. Epub 2019 Oct 24. Cancer Discov. 2020. PMID: 31649109 Free PMC article.
Drugging RAS: Know the enemy.
Papke B, Der CJ. Papke B, et al. Science. 2017 Mar 17;355(6330):1158-1163. doi: 10.1126/science.aam7622. Epub 2017 Mar 16. Science. 2017. PMID: 28302824 Review.
Post-translational modification of RAS proteins.
Campbell SL, Philips MR. Campbell SL, et al. Curr Opin Struct Biol. 2021 Dec;71:180-192. doi: 10.1016/j.sbi.2021.06.015. Epub 2021 Aug 6. Curr Opin Struct Biol. 2021. PMID: 34365229 Free PMC article. Review.
RHOA takes the RHOad less traveled to cancer.
Schaefer A, Der CJ. Schaefer A, et al. Trends Cancer. 2022 Aug;8(8):655-669. doi: 10.1016/j.trecan.2022.04.005. Epub 2022 May 12. Trends Cancer. 2022. PMID: 35568648 Review.
The role of wild type RAS isoforms in cancer.
Zhou B, Der CJ, Cox AD. Zhou B, et al. Semin Cell Dev Biol. 2016 Oct;58:60-9. doi: 10.1016/j.semcdb.2016.07.012. Epub 2016 Jul 13. Semin Cell Dev Biol. 2016. PMID: 27422332 Free PMC article. Review.
60 results