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Page 1
APOBECs and Herpesviruses.
Cheng AZ, Moraes SN, Shaban NM, Fanunza E, Bierle CJ, Southern PJ, Bresnahan WA, Rice SA, Harris RS. Cheng AZ, et al. Viruses. 2021 Feb 28;13(3):390. doi: 10.3390/v13030390. Viruses. 2021. PMID: 33671095 Free PMC article. Review.
APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer.
McCann JL, Cristini A, Law EK, Lee SY, Tellier M, Carpenter MA, Beghè C, Kim JJ, Sanchez A, Jarvis MC, Stefanovska B, Temiz NA, Bergstrom EN, Salamango DJ, Brown MR, Murphy S, Alexandrov LB, Miller KM, Gromak N, Harris RS. McCann JL, et al. Nat Genet. 2023 Oct;55(10):1721-1734. doi: 10.1038/s41588-023-01504-w. Epub 2023 Sep 21. Nat Genet. 2023. PMID: 37735199 Free PMC article.
Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Harjes S, Kurup HM, Rieffer AE, Bayarjargal M, Filitcheva J, Su Y, Hale TK, Filichev VV, Harjes E, Harris RS, Jameson GB. Harjes S, et al. Nat Commun. 2023 Oct 11;14(1):6382. doi: 10.1038/s41467-023-42174-w. Nat Commun. 2023. PMID: 37821454 Free PMC article.
Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.
Shichijo T, Yasunaga JI, Sato K, Nosaka K, Toyoda K, Watanabe M, Zhang W, Koyanagi Y, Murphy EL, Bruhn RL, Koh KR, Akari H, Ikeda T, Harris RS, Green PL, Matsuoka M. Shichijo T, et al. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2309925121. doi: 10.1073/pnas.2309925121. Epub 2024 Mar 19. Proc Natl Acad Sci U S A. 2024. PMID: 38502701 Free PMC article.
Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Venkatesan S, Angelova M, Puttick C, Zhai H, Caswell DR, Lu WT, Dietzen M, Galanos P, Evangelou K, Bellelli R, Lim EL, Watkins TBK, Rowan A, Teixeira VH, Zhao Y, Chen H, Ngo B, Zalmas LP, Al Bakir M, Hobor S, Grönroos E, Pennycuick A, Nigro E, Campbell BB, Brown WL, Akarca AU, Marafioti T, Wu MY, Howell M, Boulton SJ, Bertoli C, Fenton TR, de Bruin RAM, Maya-Mendoza A, Santoni-Rugiu E, Hynds RE, Gorgoulis VG, Jamal-Hanjani M, McGranahan N, Harris RS, Janes SM, Bartkova J, Bakhoum SF, Bartek J, Kanu N, Swanton C; TRACERx Consortium. Venkatesan S, et al. Cancer Discov. 2021 Oct;11(10):2456-2473. doi: 10.1158/2159-8290.CD-20-0725. Epub 2021 May 4. Cancer Discov. 2021. PMID: 33947663 Free PMC article.
Acute expression of human APOBEC3B in mice results in RNA editing and lethality.
Alonso de la Vega A, Temiz NA, Tasakis R, Somogyi K, Salgueiro L, Zimmer E, Ramos M, Diaz-Jimenez A, Chocarro S, Fernández-Vaquero M, Stefanovska B, Reuveni E, Ben-David U, Stenzinger A, Poth T, Heikenwälder M, Papavasiliou N, Harris RS, Sotillo R. Alonso de la Vega A, et al. Genome Biol. 2023 Nov 24;24(1):267. doi: 10.1186/s13059-023-03115-4. Genome Biol. 2023. PMID: 38001542 Free PMC article.
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA.
Bergstrom EN, Luebeck J, Petljak M, Khandekar A, Barnes M, Zhang T, Steele CD, Pillay N, Landi MT, Bafna V, Mischel PS, Harris RS, Alexandrov LB. Bergstrom EN, et al. Nature. 2022 Feb;602(7897):510-517. doi: 10.1038/s41586-022-04398-6. Epub 2022 Feb 9. Nature. 2022. PMID: 35140399 Free PMC article.
70 results