P01 GM032165/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2002	1
2004	1
2006	5
2007	4
2008	12
2009	10
2010	17
2011	23
2012	20
2013	12
2014	8
2015	6
2016	2
2018	1
2020	1
2021	1
2022	3
2023	1
2025	0

1

Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs.

Ritchie TK, Grinkova YV, Bayburt TH, Denisov IG, Zolnerciks JK, Atkins WM, Sligar SG. Ritchie TK, et al. Methods Enzymol. 2009;464:211-31. doi: 10.1016/S0076-6879(09)64011-8. Methods Enzymol. 2009. PMID: 19903557 Free PMC article.

2

Rearrangement reactions catalyzed by cytochrome P450s.

Ortiz de Montellano PR, Nelson SD. Ortiz de Montellano PR, et al. Arch Biochem Biophys. 2011 Mar 1;507(1):95-110. doi: 10.1016/j.abb.2010.10.016. Epub 2010 Oct 29. Arch Biochem Biophys. 2011. PMID: 20971058 Free PMC article. Review.

3

Interactions of cytochrome P450s with their ligands.

Conner KP, Woods CM, Atkins WM. Conner KP, et al. Arch Biochem Biophys. 2011 Mar 1;507(1):56-65. doi: 10.1016/j.abb.2010.10.006. Epub 2010 Oct 19. Arch Biochem Biophys. 2011. PMID: 20939998 Free PMC article. Review.

4

Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib.

Ho HK, Chan JC, Hardy KD, Chan EC. Ho HK, et al. Drug Metab Rev. 2015 Feb;47(1):21-8. doi: 10.3109/03602532.2014.1003648. Epub 2015 Feb 2. Drug Metab Rev. 2015. PMID: 25639891 Free PMC article. Review.

5

Drug interactions at the blood-brain barrier: fact or fantasy?

Eyal S, Hsiao P, Unadkat JD. Eyal S, et al. Pharmacol Ther. 2009 Jul;123(1):80-104. doi: 10.1016/j.pharmthera.2009.03.017. Epub 2009 Apr 22. Pharmacol Ther. 2009. PMID: 19393264 Free PMC article. Review.

6

Rationalization and prediction of in vivo metabolite exposures: the role of metabolite kinetics, clearance predictions and in vitro parameters.

Lutz JD, Fujioka Y, Isoherranen N. Lutz JD, et al. Expert Opin Drug Metab Toxicol. 2010 Sep;6(9):1095-109. doi: 10.1517/17425255.2010.497487. Expert Opin Drug Metab Toxicol. 2010. PMID: 20557268 Free PMC article. Review.

7

Importance of multi-p450 inhibition in drug-drug interactions: evaluation of incidence, inhibition magnitude, and prediction from in vitro data.

Isoherranen N, Lutz JD, Chung SP, Hachad H, Levy RH, Ragueneau-Majlessi I. Isoherranen N, et al. Chem Res Toxicol. 2012 Nov 19;25(11):2285-300. doi: 10.1021/tx300192g. Epub 2012 Sep 27. Chem Res Toxicol. 2012. PMID: 22823924 Free PMC article. Review.

8

Qualitative analysis of the role of metabolites in inhibitory drug-drug interactions: literature evaluation based on the metabolism and transport drug interaction database.

Isoherranen N, Hachad H, Yeung CK, Levy RH. Isoherranen N, et al. Chem Res Toxicol. 2009 Feb;22(2):294-8. doi: 10.1021/tx800491e. Chem Res Toxicol. 2009. PMID: 19216580 Free PMC article. Review.

9

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia.

Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE. Zhou C, et al. J Clin Invest. 2006 Jun;116(6):1703-12. doi: 10.1172/JCI27793. Epub 2006 May 11. J Clin Invest. 2006. PMID: 16691293 Free PMC article.

10

A Physiological-Based Pharmacokinetic Model Embedded with a Target-Mediated Drug Disposition Mechanism Can Characterize Single-Dose Warfarin Pharmacokinetic Profiles in Subjects with Various CYP2C9 Genotypes under Different Cotreatments.

Cheng S, Flora DR, Rettie AE, Brundage RC, Tracy TS. Cheng S, et al. Drug Metab Dispos. 2023 Feb;51(2):257-267. doi: 10.1124/dmd.122.001048. Epub 2022 Nov 15. Drug Metab Dispos. 2023. PMID: 36379708 Free PMC article.

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