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alpha1-Proteinase inhibitor forms initial non-covalent and final covalent complexes with elastase analogously to other serpin-proteinase pairs, suggesting a common mechanism of inhibition.
J Biol Chem. 2004 Mar 5;279(10):9264-9. doi: 10.1074/jbc.M311731200. Epub 2003 Oct 30.
J Biol Chem. 2004.
PMID: 14593107
Free article.
Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of alpha1-proteinase inhibitor with porcine pancreatic elastase.
Dementiev A, Dobó J, Gettins PG.
Dementiev A, et al.
J Biol Chem. 2006 Feb 10;281(6):3452-7. doi: 10.1074/jbc.M510564200. Epub 2005 Dec 1.
J Biol Chem. 2006.
PMID: 16321984
Free article.
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