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Targeting DNA methylation.
Issa JP, Kantarjian HM. Issa JP, et al. Clin Cancer Res. 2009 Jun 15;15(12):3938-46. doi: 10.1158/1078-0432.CCR-08-2783. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509174 Free PMC article.
Further activation of FLT3 mutants by FLT3 ligand.
Zheng R, Bailey E, Nguyen B, Yang X, Piloto O, Levis M, Small D. Zheng R, et al. Oncogene. 2011 Sep 22;30(38):4004-14. doi: 10.1038/onc.2011.110. Epub 2011 Apr 25. Oncogene. 2011. PMID: 21516120 Free PMC article.